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Cantaloupe Allergy comes in a variety of flavors.

Cantaloupe Allergy comes in a variety of flavors.

Although it is not frequently reported, cantaloupe allergies can have adverse effects. Other foods, especially bananas, cucumbers, sunflower seeds, zucchini, banana, honeydew, and watermelon, are frequently reported to cause hypersensitivity reactions. The edible cantaloupe belongs to the gourd family and is distinguished by its orange, sweet flesh and tough, scaly skin. Its scientific name is Cucumis melo cantalupensis, and Asian nations are the biggest producers. It is well-liked all over the world. Another variety of muskmelon is the cantaloupe, which has a reticulated rind and pale orange flesh.

Three Main Types Of Reactions To Cantaloupe

Oral Allergy Syndrome

Lips and tongue swelling, along with mouth itching, are common symptoms of oral allergy syndrome. Patients with ragweed pollen allergies can describe cantaloupe oral allergy syndrome symptoms. This is a cross-reactivity of the proteins to the ragweed pollen, not a true cantaloupe allergy. The following foods also fall into this category: banana, cucumber, other melons, sunflower seeds, and zucchini. Avoiding it is the only effective form of treatment.


Hives, swelling, wheezing, coughing, vomiting, diarrhea, and low blood pressure are some of the symptoms of anaphylaxis that can happen. It has been suggested that cantaloupe-specific proteins and cucumisin together cause the degranulation of IgE mast cells. To test for cantaloupe allergy, one can use allergy skin testing, particular IgE lab testing, and fresh food skin testing with cantaloupe. Three food allergens, known as Cuc m 1, m 2, and m3, are present in the muskmelon family of fruits.


The melon peel can cause dermatitis, a contact allergy that manifests as itching and redness. Skin contact allergies can be brought on by nonspecific lipid transfer protein (nsLTP), which is found in the peel.

Oral Allergy Syndrome: What Is It?

Cross-reactivity between the proteins in fresh fruits and vegetables and pollens is what causes oral allergy syndrome (OAS). Up to 70% of people who are allergic to pollen experience this syndrome. When fruits and vegetables are cooked or processed, the OAS-causing proteins in those foods are easily broken down. Therefore, fruits and vegetables that have been baked or cooked, as well as processed fruits like those found in applesauce, rarely cause OAS.

Most OAS sufferers experience symptoms like tingling, burning, itching, and occasionally swelling of the lips, mouth, tongue, and throat where fresh produce is touched.

What Is Anaphylaxis?

A rare but severe allergic reaction is anaphylaxis. It happens unexpectedly, can get worse quickly, and can even be fatal. After being exposed to a triggering agent, anaphylaxis develops. The substance triggers the body’s natural chemicals, like histamine, to release, exacerbating allergy symptoms. Epinephrine is the first line of medication for anaphylaxis.

What causes my anaphylactic reaction?

Any substance or food that you came into contact with just before the anaphylactic reaction began is a potential trigger. Make a very thorough list, and bring it with you to your doctor’s appointment. An allergist can frequently assist you in identifying the cause of your anaphylactic reaction. Tests may be performed on the skin or with blood.

What Is Dermatitis?

Dermatitis is a broad term that refers to any type of skin irritation. It has numerous causes and manifestations, but the most common are itchy, dry skin and a rash. Alternatively, it may cause the skin to blister, ooze, crust, or flake off. Atopic dermatitis (eczema), seborrheic dermatitis, and contact dermatitis are the three most common types of this condition.

Dermatitis is not contagious, but it can cause discomfort and self-consciousness. Moisturizing regularly aids in symptom control. Medicated ointments, creams, and shampoos may also be used in treatment.

Expert Help From Allergy, Asthma, and Immunology Medical Group

Cantaloupe reactions can thus take various forms. An allergy doctor can help determine what type of reaction one has to cantaloupe and perform the necessary tests to confirm or rule out a clinical allergy diagnosis. Call 805-658-9500 today and take the first step toward allergy relief.