Managing Severe Eczema with Biologic Treatments

Eczema, also known as atopic dermatitis, is more than just a skin condition. For people living with moderate to severe eczema, daily life can be filled with itching, redness, pain, and embarrassment. Flare-ups often interfere with sleep, work, and social interactions, leaving many patients searching for lasting relief.

Traditional treatments such as topical creams or oral medications may help some people, but they are not always enough. For those struggling with severe, persistent symptoms, biologic therapies offer a breakthrough. At Allergy, Asthma, and Immunology Medical Group, we prescribe FDA-approved biologics like Dupixent to help patients take control of their eczema and restore quality of life.

Understanding Severe Eczema

Eczema occurs when the immune system overreacts, triggering chronic inflammation in the skin. This inflammation causes hallmark symptoms such as:

• Red, itchy, or scaly patches
• Cracked or oozing skin
• Painful flare-ups that resist standard treatment
• Thickened skin from repeated scratching

Severe eczema is especially challenging because flare-ups can cover large areas of the body and may not respond to topical treatments alone.

How Biologics Work

Biologics are advanced medications made from living cells. Unlike topical creams that target surface symptoms, biologics target the immune system directly. They block the proteins responsible for inflammation, reducing the immune system’s overreaction and easing symptoms from within.

For eczema, Dupixent is one of the most widely used biologics. It works by blocking two specific proteins, IL-4 and IL-13, which are key drivers of the inflammatory response that leads to eczema symptoms.

Benefits of Biologic Therapy for Eczema

Patients who qualify for biologic treatment often experience significant improvements, including:

• Reduced skin inflammation and redness
• Relief from persistent itching
• Improved sleep and comfort
• Fewer flare-ups over time
• Enhanced quality of life with restored confidence

Unlike some systemic medications, Dupixent can be self-administered at home with injections, making it a convenient option for long-term care.

Who Qualifies for Biologics?

Biologics are typically recommended for individuals who:

• Have moderate to severe eczema that hasn’t improved with topical treatments
• Experience frequent flare-ups that disrupt daily life
• Suffer from side effects caused by other medications
• Need a long-term treatment plan for ongoing management

At Allergy, Asthma, and Immunology Medical Group, our allergists and immunologists perform thorough evaluations to determine whether a biologic is the right step.

Safety and Side Effects

Like all medications, biologics come with potential side effects. For Dupixent, the most common include injection site reactions, eye irritation, or cold-like symptoms. Serious side effects are rare, and because the treatment targets specific immune pathways, it generally has fewer risks than broad-spectrum oral medications such as steroids.

Regular follow-ups allow our doctors to monitor your progress and adjust treatment if necessary, ensuring both safety and effectiveness.

The Importance of Specialist Care

Managing eczema isn’t just about controlling flare-ups—it’s about finding a long-term solution that improves overall health. At Allergy, Asthma, and Immunology Medical Group, we provide:

• Accurate diagnosis and testing to confirm eczema severity
• Access to advanced therapies like Dupixent
• Personalized care plans tailored to each patient
• Ongoing support to monitor effectiveness and manage side effects

Our goal is to help patients achieve healthier skin and a better quality of life with the latest evidence-based treatments.

A New Way Forward for Eczema Patients

Living with severe eczema can feel exhausting, but you don’t have to manage it alone. Biologic therapies like Dupixent represent a new frontier in care, offering relief where traditional treatments fall short. By targeting the root cause of inflammation, biologics help restore comfort, confidence, and control.

If you’re ready to explore options beyond topical creams, contact Allergy, Asthma, and Immunology Medical Group at 805-658-9500 today to schedule an appointment. Our specialists will work with you to determine if biologic therapy is the right step toward lasting relief.